The mighty Mekong flows for almost 3,000 miles — from China through Laos and into Cambodia and Vietnam — and is one of the world’s great river systems. It forms the borders between countries in Southeast Asia and many of the region’s oldest cities have been built on or near its banks and those of its tributaries. A visual tapestry of vivid green rice paddies, ancient temples, floating markets, ramshackle villages, and former royal residences makes for a fascinating cultural journey. The majority of Mekong River cruises focus on the section between Siem Reap (Cambodia) and Ho Chi Minh City (Vietnam) from August to April, since the weather is too hot and river levels are too low from May to July.